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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
27.58
Human Site:
T474
Identified Species:
50.56
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
T474
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
T488
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
T474
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Dog
Lupus familis
XP_537704
2182
240593
T483
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
T474
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Rat
Rattus norvegicus
NP_001100505
2040
223488
N379
D
S
Q
V
R
F
T
N
I
R
T
N
D
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
T470
K
P
Q
K
R
P
L
T
P
F
H
H
R
A
S
Chicken
Gallus gallus
XP_415884
2225
244861
T518
K
P
Q
K
R
P
L
T
P
F
H
H
R
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
S420
F
V
E
S
S
Q
R
S
Q
C
S
C
S
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
Q545
Q
Q
Q
I
Q
Q
Q
Q
Q
R
Q
K
L
W
N
Honey Bee
Apis mellifera
XP_393643
1982
216109
A321
L
S
P
P
S
S
P
A
S
C
E
H
P
L
L
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
K606
I
G
P
I
T
P
R
K
A
G
D
S
V
K
Q
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
93.3
100
N.A.
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
93.3
100
N.A.
13.3
N.A.
26.6
13.3
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
54
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
54
62
0
0
0
% H
% Ile:
8
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
54
0
0
54
0
0
0
8
0
0
0
8
0
8
0
% K
% Leu:
8
0
0
0
0
0
54
0
0
0
0
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% N
% Pro:
0
54
16
8
0
62
8
0
54
0
0
0
8
0
0
% P
% Gln:
8
8
70
0
8
16
8
8
16
0
8
0
0
0
8
% Q
% Arg:
0
0
0
0
62
0
16
0
0
16
0
0
54
8
0
% R
% Ser:
0
16
0
8
16
8
0
8
8
0
8
8
8
0
54
% S
% Thr:
0
0
0
0
8
0
8
54
0
0
8
0
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
0
8
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _